Ketamine

Administration
•Initial dose: 1-2 mg/kg IV slow push •CI: 0.5-7.5 mg/kg/hr •Titrate by 0.5 mg/kg/hr every 10 minutes
Consideration
•Maximal effect in 1 minute •Hepatic metabolism to active metabolite norketamine •Favorable hemodynamic effects •Minimal respiratory effects
Adverse Effects
•Agitation with auditory and visual hallucinations •Conscious vivid dreams •Increased intracranial pressure •Tachyarrhythmias •Hypersalivation