NPH (Slow onset, progressive)

Clinical presentation
Characterized by gait abnormality, urinary incontinence, and cognitive impairment, with ventriculomegaly.
Dilated ventricles on MRI, negligible cortical atrophy. Fluorodopa PET - decreased blood flow to basal ganglia. DaT Scan - reduced uptake in Striatum .
Increased strain in the periventricular area, and insufficient blood supply to basal ganglia (especially nigrostriatal connections).
Associated features
Parkinsonism, hypokinesia mainly, may be the presenting feature. Shuffling gait is observed.

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