Enhanced physiological tremor is the most commonly observed postural tremor. Physiologic tremor is undetectable, low amplitude and high frequency (10-12 Hz) tremor in normal individuals. Sympathetic hyperactivity causes enhanced physiological tremor that can be detected on observation.
Restless legs syndrome (RLS) (also known as Willis-Ekbom disease) is characterized by an intense crawling sensation deep inside the lower legs. Most cases are familial but can be secondary to an underlying illness. Management includes treating underlying diseases, nonpharmacologic therapy, and pharmacological therapy. Severe RLS may spread to the arms and significantly reduce the quality of life. This chapter discusses etiology, pathophysiology, clinical features, diagnostic evaluation, and management of RLS.
It is an Autosomal Recessive trait, also known as Progressive Hepatolenticular Degeneration. Liver biopsy is the single most sensitive and accurate investigation for the disease. Males are more likely to develop neuropsychiatric disease, whereas females are more likely to develop acute liver failure due to Wilson's disease.
Parkinson's Disease is a neurodegenerative disorder that has historically been seen as a motor disorder. However, there are significant non-motor symptoms in almost all of the patients with PD. Including frequent Psychiatric Co-morbidities both in early and late PD