Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare immune-mediated disorder affecting the peripheral nervous system. Typical manifestations include proximal and distal sensory and motor impairment in four limbs, developing over more than eight weeks.
Also known as Weston-Hurst syndrome most commonly affects the cerebrum followed by the cerebellum, brain stem, or spinal cord. As its pathogenesis involves progressive hemorrhagic demyelination of white matter, MRI is considered the diagnostic test of choice to detect any diffuse edema, confluent lesions, or petechial hemorrhage. Failure to provide early treatment will result in a poor prognosis or even death in a few days.
Facial (nerve) palsy is a neurological condition that is commonly categorized as central or peripheral based on the location of the lesion. Symptoms and signs experienced by the patient help in diagnosing the area of the lesion. In idiopathic facial nerve palsy, the extent of nerve damage determines the outcome. In this chapter, we focus on discussing symptoms to distinguish both types of facial palsy along with management and prognosis of the disease
CNS vasculitis is classified as Primary angiitis of CNS, Systemic vasculitis involving CNS, Secondary (Secondary CNS vasculitis). Treatment is aggressive for the first 6-8 months and then tapered depending upon the resolution of symptoms. Monitoring of treatment is necessary. MRI should be done after 4-6 weeks of initiation of therapy and afterward done every 3-4 months in the first year of treatment.